Tablet grinding and dissolving for subsequent analysis:
Pharmacopoeia Tests, as described in official compendia are standardized test procedures which have clearly stated limits under which compressed tablets could be accepted.
The crushing and dissolving of tablets and capsules is typically an initial step prior to the analysis methods used to find the content of active ingredient. Other similar tests which use this preliminary grinding and dissolution also include:
› Uniformity of Weight
› Uniformity of Content
› Disintegration time test
› Dissolution test
Challenges in the preliminary grinding and dissolution of tablets include preventing the risk of cross contamination between sample batches and the lengthy cleaning processes of mills, grinders and containers in which the tests are performed.
With the ULTRA-TURRAX® Tube Drive IKA offers a powerful, universal shredding drive that is operated in combination with patented disposable plastic containers.
The crushing and dissolving of tablets and capsules can take place in a single-use tube with no risk of cross contamination between sample sets and no need for cleaning the grinding device. The subsequent transport to the laboratory analysis machines or downstream processes take place in a hermetically sealed container.
The samples can then be taken via the pierceable membrane in the sample lid.
The lockable disposable sample containers are transport containers, comminution containers and storage all in one. They significantly reduce the cleaning effort and systematically rule out cross-contamination. Users benefit from reduced handling costs and a reduced number of incorrect analyses.
Included in this package:
• ULTRA-TURRAX® Tube Drive P Control
• Pack with 10 DIS-300-S-M.10 dissolver tubes, 300ml (0020016318)
We would be happy to advise you.
You can find more tube options in the accessories section.
You can find the drive without tubes here: LINK
The 300ml disposable tube DIS-300-S is equipped with a dissolver blade and opens up new application fields. It was designed for dissolving samples in different solvents.
For a list of suitable solvents refer to the manual.
Suitable with ULTRA-TURRAX® Tube Drive P control
Tube for ULTRA-TURRAX® Tube Drive P control
• Volume [mL]: 300
• Working range [mL]: 50 - 250
• Functional unit: Dissolver, stainless steel
• Membrane lid: yes
• Sterile: no
• IVD label: no
• Packaging unit [pcs.]: 10
• Application: crushing, mixing, dissolve
• Application example: Dissolving of tablets or capsules in solvents